Pseudo SARS-CoV-2 D614G Mutation Red Reporter #C1120R
Baculovirus pseudotyped with SARS-CoV-2 D614G mutated spike protein that binds with ACE2 and expresses red fluorescent protein at the nucleus 24 hours after viral entry.
SARS-CoV-2 assays and reagents
Baculovirus vector pseudotyped with D614G mutated SARS-CoV-2 spike protein:
D614G Pseudo SARS-CoV-2 is a BSL-1 baculovirus pseudotyped with D614G spike isolate. Pseudovirus enters the host cell through interactions with ACE2 and other host proteins, then delivers a reporter that expresses bright red fluorescence in the host cell nucleus. When viral entry is successfully blocked, the host fluorescence is decreased.
D614G PseudoSARS-CoV-2 is pseudotyped with the D614G variant of the SARS-CoV-2 spike protein. This European isolate spike protein decorates the surface of the pseudovirus, facilitating entry into cells expressing ACE2.
- Detect host-pathogen interaction in living cells.
- Identify therapeutic drugs that block ACE2-mediated viral entry.
- Cost effective screening with minimal safety requirements (BSL-2).
Materials in the Kit:
• D614G Pseudo SARS CoV-2 Red NLS
• Sodium Butyrate, 500 mM in H2O
• Detailed protocol
This SARS-CoV-2 Reporter is currently backordered . Please contact us if interested in ordering this kit.
Product Info & Protocols
| Protocol for Use | https://montanamolecular.com/fluorescent-pseudo-sars-cov-2-reporter-protocol/ |
|---|---|
| Shipping | We strive for prompt delivery of each order, so we ship by FedEx 2-day service in lightweight, sturdy, and reusable packaging with an insulated cooler and moisture-resistant refrigerant gel packs. Shipping days are Mon-Wed so product does not sit in transit over the weekend. Web store ships to US & Canada only, contact sales for other locations. Purchases over $600 receive free shipping. |
| MSDS | https://montanamolecular.com/wp-content/uploads/2020/05/Pseudo-SARS-CoV-2-MSDS-PDF.pdf |
| Kit Volume | 5mL, 30mL, 60mL |
| More Info |
