If you will be attending the Biophysical Society’s Annual Meeting, don’t miss our presentation: Membrane Biophysics Subgroup 2017 Symposium Saturday, February 11, 2017 Room R02/03 Visualizing the competition between Gs and Gi signaling at the membrane...
Measuring dynamic and real-time cAMP levels using cADDis Real-Time cAMP Detection Here, we introduce a new fluorescent cAMP sensor, cADDis, capable of detecting dynamic changes in cAMP concentration in living cells. We have applied cADDis to use in a novel Gi assay...
cADDis – A New Handle on Cilia Signaling The Proceedings of the National Academy of Sciences published another new scientific breakthrough made possible with our cADDis fluorescent biosensors. Our sensors indicate changes in cell signals with changes in...
GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation A new Journal of Clinical Investigation paper from Patrik Rorsman’s group provides key insights into signaling mechanisms of GLP-1, a peptide that enhances insulin secretion and is...