Try Red cADDis, a bright red single fluorescent protein biosensor for cAMP, in any cell type with blue light-activated adenylyl cyclase to study cAMP dynamics without using drugs.

  • Bypass the GPCR with a pulse of light to cells expressing bPAC.
  • 470 nm wavelenght of light stimulates cAMP response and robust changes in fluorescence.
  • Image red fluorescence in living cells with 556 nm excitation and 620 nm emission.

Click the poster thumbnail to check out:  Toward a High Throughput Screen for Voltage Sensors

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