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Montana Molecular News

 

A Rapid and Sensitive Approach to Detecting SARS-CoV-2

A Rapid and Sensitive Approach to Detecting SARS-CoV-2

There is a race in this pandemic to develop new technologies to detect SAR-CoV-2 virus and defeat its spread as quickly as possible. A bright light in this race recently appeared in a new paper published by Nanoscale Advances that describes a simple,...

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The Neuroscience of Nausea

The Neuroscience of Nausea

Nausea is a sense of malaise that all of us know. The sensation can be so overpowering that it leads us to wonder how and why this wretched condition happens

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SARS-CoV-2 Variant Pseudoviruses

SARS-CoV-2 Variant Pseudoviruses

At Montana Molecular, we are committed to developing validated tools and services to support COVID-19 drug discovery. 2nd generation pseudoviruses for SARS-CoV-2 variants are on the way. Emerging SARS CoV-2 VariantsIn the spring of 2020, Manaus Brazil, was...

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Covid 19 Drug Discovery Services

Covid 19 Drug Discovery Services

Functional Cell-based Assays Verified & Compound Libraries  This unique platform is a powerful resource for researchers developing 3CLpro inhibitors and can streamline the development of safe and effective therapeutic treatments for...

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Mpro inhibitor saves cats from certain death

Mpro inhibitor saves cats from certain death

Feline Infectious Peritonitis (FIP) is caused by a coronavirus. The 3CLpro of this virus is much like the one in SARS-CoV-2 and is crucial for viral replication. In 2016, Kim and colleagues showed that the compound GC376 blocked viral replication in cats...

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SARS-CoV-2 Pseudovirus Entry Assay

SARS-CoV-2 Pseudovirus Entry Assay

Overview of SARS-CoV-2 Viral Entry The generally accepted model for SARS-CoV-2 viral entry involves two crucial elements: the Spike protein on the surface of the enveloped virus, and the host receptor ACE2.  The Spike protein has a high...

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SARS-CoV-2 Pseudovirus (Update)

SARS-CoV-2 Pseudovirus (Update)

Thank you for your interest in Montana Molecular’s assays for SARS-CoV-2 research and drug discovery. In a rapidly evolving field, as new insights into the mechanisms of viral entry come to light, we sincerely appreciate your patience and feedback as we continue to...

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Live Cell Assays for COVID-19 Drug Screening

Live Cell Assays for COVID-19 Drug Screening

COVID-19 continues to disrupt life as we know it, but here in Montana we are devising a new brand of biosensors for our heroes who are testing antivirals to fight SARS-CoV-2. Here’s what’s in our pipeline for targeting viral entry into host cells.  ...

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