GPCR Biology

G-Protein Coupled Receptors (GPCRs) are one of the largest receptor families in the genome and are essential for the healthy function of nearly every organ in the body. GPCRs are also important targets for therapeutic drugs. Increase your understanding of drug effects and GPCR biology with bright fluorescent assays in living cells.

GPCR Biology

G-Protein Coupled Receptors (GPCRs) are one of the largest receptor families in the genome and are essential for the healthy function of nearly every organ in the body. GPCRs are also important targets for therapeutic drugs. Increase your understanding of drug effects and GPCR biology with bright fluorescent assays in living cells.

Simultaneous detection of GPCR second messengers in living HEK 293 cells; By combining red and green sensors in a single transduction step, changes in two second messengers can be detected simultaneously. Green sensors in the top panels, red sensors in the bottom panels. M1 muscarinic receptor activated by carbachol.

GPCR Assays in Living Cells

Monitor PIP2 in Living Cells

PIP2 Assays