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#V0100N bPAC Enzyme

$595.00

The light activated bPAC enzyme (#V0100N) is an adenylyl cyclase that, when stimulated with blue light, will rapidly create cAMP.


Featured Publication:

Alkyne-Tagged Dopamines as Versatile Analogue Probes for Dopaminergic System Analysis

Use blue light to control intracellular cAMP, express bPAC in mammalian cells. The light activated bPAC enzyme (#V0100N) is an adenylyl cyclase that, when stimulated with blue light, will rapidly create cAMP. Packaged in BacMam for consistent, titratable expression across a wide range of cell types. More information and example data can be found on the Optogenetic Toolkit page.


Materials in the Kit:

• bPAC enzyme in BacMam

• Sodium Butyrate, 500 mM in H2O

Additional information

Shipping

We strive for prompt delivery of each order, so we ship by FedEx 2-day service in lightweight, sturdy, and reusable/biodegradable packaging with an insulated cooler and moisture-resistant refrigerant gel packs. Shipping days are Mon-Wed so product does not sit in transit over the weekend. Web store ships to US & Canada only, contact sales for other locations.

Protocol for Use

https://montanamolecular.com/general-bacmam-transduction-protocol/

MSDS

https://montanamolecular.com/msds-for-optogenetic-tools/

Sequence Reference Number

PDB:5M27_A

Scientific Publications

Light Modulation of Cellular cAMP by a Small Bacterial Photoactivated Adenylyl Cyclase, bPAC, of the Soil Bacterium Beggiatoa http://www.jbc.org/content/286/2/1181.full

Optogenetic Approaches to Drug Discovery in Neuroscience and Beyond. https://www.ncbi.nlm.nih.gov/pubmed/28552428

Kit Volume

10mL