New Fluorescent Tools to Monitor Cell Stress and Toxicity
This biosensor allows real-time monitoring of genetically or chemically induced cell stress and drug induced cellular toxicity in under 24 hours. It can be combined with second messenger biosensors to simultaneously monitor cell signaling in stressed and healthy...
Transgenic DAG Sensors
Check out this paper, just published in Cell Reports, about measuring DAG at the synapse in sensory neurons: Dynamics of Presynaptic Diacylglycerol in a Sensory Neuron Encode Differences between Past and Current Stimulus Intensity H. Ohno, N. Sakai, T. Adachi, Y, Iino...
Fluorescent Biosensors Reveal the Inner Workings of Living Cells
Fluorescent Biosensors Reveal the Inner Workings of Living Cells Anne Marie Quinn, founder of Montana Molecular, shares how it’s possible to measure, in real time, multiple signaling pathways inside a living cell 12 Jul 2017 G protein-coupled receptors (GPCRs) form...
Human Beta Cells Produce and Release Serotonin to Inhibit Glucagon Secretion from Alpha Cells
A mystery about hormone regulation in pancreatic islet cells is solved with cADDis! Researchers at University of Miami made good use of Montana Molecular’s cADDis assay for cAMP to study how islet cells respond to glucose. This elegant article in Cell Reports authored...