Montana Molecular News
cADDis – A New Handle on Cilia Signaling
The Proceedings of the National Academy of Sciences published another new scientific breakthrough made possible with our cADDis fluorescent biosensors. Montana Molecular’s genetically-encoded fluorescent biosensors are designed to indicate changes in cell signals with changes in fluorescence intensity and provide a window into the hidden machinery of the living cell.
BIO International Convention 2016
Wednesday June 8, 2016 11:30 am, Room 3
GLP-1 sends PKC-dependent signals
GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation A new Journal of Clinical Investigation paper from Patrik Rorsman's group provides key insights into signaling mechanisms of GLP-1, a peptide that enhances insulin secretion and is the...
Basel Life Science Week
Basel Life Science Week Montana Molecular's own Dr. T. Hughes will be presenting at the Basel Life Science Week GPCR Forum in Basel, Switzerland. Fluorescent biosensors for multicolored views of GPCR signaling will be presented at 11am, Sept. 24, 2015 in Room 4 at the...
ArcLight Voltage Sensor
ArcLight Voltage Sensor[fruitful_sep] A genetically-encoded, fluorescent voltage sensing protein in a BacMam viral delivery system is a noninvasive, easy-to-use tool for studying the electrical activity of live neurons. To learn more about the development of voltage...
FPX Biosensors for Live Cell Imaging Published
First there was FRET, now there is FPX
Drug Discovery News
Biotek Scientific Director likes Montana Molecular’s live cell assays: “These sensors can be used for the simultaneous detection of all these second messengers. That is something that is really unique and really powerful, specifically for drug discovery efforts for GPCRs.”
PHASE II SBIR Funding Awarded to Montana Molecular
$1.1 million investment from the National Institutes of Health advances next generation tools for drug discovery in living cells. Montana Molecular, a privately-held company developing next generation tools for drug discovery in living cells, has been...
DAG sensor and μ-opioid receptor desensitization
Early adopters of Montana Molecular’s DAG sensor at The Vollum Institute published new results in the British Journal of Pharmacology. This study made good use of our Upward DAG sensor for diacylglycerol…
DAG sensor illuminates TRPC6 Regulation
Montana Molecular’s DAG sensor helped unravel the molecular mechanisms of TRPC6 cation channel activity which could lead to new treatments for TRPC6-associated diseases that affect cardiovascular and kidney dysfunction…
