A mystery about hormone regulation in pancreatic islet cells is solved with cADDis!

Researchers at University of Miami made good use of Montana Molecular’s cADDis assay for cAMP to study how islet cells respond to glucose. This elegant article in Cell Reports authored by Joana Almaça and her colleagues at the University of Miami describes how cAMP signals were captured in live human pancreatic islet cells using cADDis, one of our suite of fluorescent biosensor assays for cell signaling.

Our cADDis cAMP Sensor- A New Handle on Cilia Signaling

Read about the latest scientific breakthrough made possible with cADDis, one of our genetically-encoded fluorescent biosensors.  Our  sensors indicate changes in cell signals with changes in fluorescence intensity and provide a window into the hidden machinery of the living cell.

Introducing cADDis: The brightest live cell assay in the world for measuring cAMP.

Make biological measurements of Gs & Gi in real time in the living cells of your choice. Save time & money with a simple, robust assay that can be detected on any fluorescence platereader or microscope. Easy steps, low cost of entry, unprecedented signal to noise.

Our live cell assays play a key role in diabetes research

Oxford University researchers recently published new findings about the mechanism that mediates insulin secretion in pancreatic β cells.
Try our assays now. Make discoveries.

ArcLight Voltage Sensor

A  genetically-encoded, fluorescent voltage sensing protein in a BacMam viral delivery system is a noninvasive, easy-to-use tool for studying the electrical activity of live neurons.

Simultaneous Detection of Multiple Signals in Living Cells

Imagine a GPCR assay that can monitor multiple second messengers in real time. Get pathway specificity with simultaneous readouts of  multiple second messengers.

Robust Fluorescent Live-Cell Assays

 

Check out our paper in Journal of Biomolecular Screening.