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GLP-1 sends PKC-dependent signals

GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation A new Journal of Clinical Investigation paper from Patrik Rorsman’s group provides key insights into signaling mechanisms of GLP-1, a peptide that enhances insulin secretion and is...

Basel Life Science Week

Basel Life Science Week Montana Molecular’s own Dr. T. Hughes will be presenting at the Basel Life Science Week GPCR Forum in Basel, Switzerland. Fluorescent biosensors for multicolored views of GPCR signaling will be presented at 11am, Sept. 24, 2015 in Room 4...

ArcLight Voltage Sensor

ArcLight Voltage Sensor[fruitful_sep] A  genetically-encoded, fluorescent voltage sensing protein in a BacMam viral delivery system is a noninvasive, easy-to-use tool for studying the electrical activity of live neurons.  To learn more about the development of voltage...

FPX Biosensors for Live Cell Imaging Published

FPX Biosensors for Live Cell Imaging Published It is always a pleasure to collaborate with our neighbors at University of Alberta! As the Campbell Lab  so succinctly summarized this work: “First there was FRET, now there is FPX!” Many thanks to Yidan Ding,...

Drug Discovery News

Drug Discovery News Biotek Scientific Director likes Montana Molecular’s live cell assays: “These sensors can be used for the simultaneous detection of all these second messengers. That is something that is really unique and really powerful, specifically for...