Montana Molecular News
New Fluorescent Tools to Monitor Cell Stress and Toxicity
This biosensor allows real-time monitoring of genetically or chemically induced cell stress and drug induced cellular toxicity in under 24 hours. It can be combined with second messenger biosensors to simultaneously monitor cell signaling in stressed and...
Transgenic DAG Sensors
Check out this paper, just published in Cell Reports, about measuring DAG at the synapse in sensory neurons: Dynamics of Presynaptic Diacylglycerol in a Sensory Neuron Encode Differences between Past and Current Stimulus Intensity H. Ohno, N. Sakai, T. Adachi, Y, Iino...
Fluorescent Biosensors Reveal the Inner Workings of Living Cells
Fluorescent Biosensors Reveal the Inner Workings of Living Cells Anne Marie Quinn, founder of Montana Molecular, shares how it’s possible to measure, in real time, multiple signaling pathways inside a living cell 12 Jul 2017 G protein-coupled receptors (GPCRs) form...
Human Beta Cells Produce and Release Serotonin to Inhibit Glucagon Secretion from Alpha Cells
A mystery about hormone regulation in pancreatic islet cells is solved with cADDis! Researchers at University of Miami made good use of Montana Molecular’s cADDis assay for cAMP to study how islet cells respond to glucose. This elegant article in Cell Reports authored...
BIO International Convention 2017
The largest, most influential biotech Convention in the world is coming to San Diego, June 19-22, 2017. Montana Molecular will be there in the NIH Innovation Zone showcasing our best and brightest live cell assays. “NIH strongly believes in supporting innovative and...
Experimental Biology 2017
A few of our esteemed colleagues will be discussing their work with our cADDis sensor at Experimental Biology in Chicago. Attending the meeting? Check out these presentations! Oral Session: cAMP Signaling Compartment: Adenylyl Cyclases as the Anchors....
Biophysical Society 61st Annual Meeting
If you will be attending the Biophysical Society's Annual Meeting, don't miss our presentation: Membrane Biophysics Subgroup 2017 Symposium Saturday, February 11, 2017 Room R02/03 Visualizing the competition between Gs and Gi signaling at the membrane Thomas Hughes,...
Measuring dynamic and real-time cAMP levels
Measuring dynamic and real-time cAMP levels using cADDis Real-Time cAMP Detection Here, we introduce a new fluorescent cAMP sensor, cADDis, capable of detecting dynamic changes in cAMP concentration in living cells. We have applied cADDis to use in a novel Gi assay...
ASCB 2016
We are showcasing our newest and brightest live cell fluorescent indicators for cell signaling at ASCB 2016. Happening at ASCB 2016 Annual Meeting: Theater 2 Tech Talk: Monday Dec. 5, 8:30 - 8:45am “Measuring dynamic cAMP levels with improved sensitivity using cADDis,...
cADDis – A New Handle on Cilia Signaling
The Proceedings of the National Academy of Sciences published another new scientific breakthrough made possible with our cADDis fluorescent biosensors. Montana Molecular’s genetically-encoded fluorescent biosensors are designed to indicate changes in cell signals with changes in fluorescence intensity and provide a window into the hidden machinery of the living cell.
