Montana Molecular News
2012 Nobel prize for GPCR studies
2012 Nobel Prize Congratulations to Bob Lefkowitz and his one-time student Brian Kobilka for winning this year's 2012 Nobel Prize in Chemistry! Not only did these laureates do groundbreaking work on the beta adrenergic receptor, but they have...
Sensing voltage on Electric Peak
Made in Montana, Electric Peak is the fastest genetically encoded voltage sensor to date, and is brought to you by Thom Hughes' Lab at Montana State University.
Better tools for drug discovery: Bozeman Chronicle, September 3, 2012
Many diseases that impact millions of people still lack effective treatments. New treatments could be developed if better tools for drug discovery were available. The more we can learn about the cell signals that impact disease and the...
Light Activated Lipids
Activating a signaling pathway with light is one of the brightest ideas to come along. Pietro de Camilli's and Bertil Hille's labs collaborated on a brilliant example of this illuminating technique! Optogenetic control of phosphoinositide metabolism describes...
Montana Molecular publishes new diacylglycerol sensor
Despite the importance to our health, the biology of how drugs work at the cellular level, remains largely a mystery. In a recent Public Library of Science (PLoS One) article, Montana Molecular describes new diacylglycerol sensors to help...
Dimerization Dependent Red Fluorescent Protein
Imagine the possibilities! In an impressive feat of rational engineering and directed evolution, Spencer C. Alford et.al. from Bob Campbell's lab at the University of Alberta developed ddRFP, a dimerization dependent bright new red that can be used to image...
Montana matches SBIR to build diacylglycerol assay
There are advantages to starting up a biotech company in Montana. For instance, companies like Montana Molecular that receive federal SBIR Phase 1 grants are eligible for state matching funds and can be used to help cover patent applications,...
Making the most of two photons
Excellent 3D resolution and minimal photobleaching made possible by multi photon microscopy are important advantages for fluorescence imaging in living cells. Until Misha Drobizhev et.al. tackled the issue, surprisingly little was known about the two photon absorption...
Montana Molecular awarded SBIR from National Institutes of Health
Montana Molecular Awarded 350K SBIR Phase 1 from NIH to develop fluorescent assays for cell-based drug discovery. BOZEMAN, MT. Montana Molecular was awarded an SBIR grant from the National Institute of Mental Health to develop fluorescent tools for...
Multicolored Calcium Imaging
Looking for inspiration? Check out Yongzin Zhao's et.al's elegant paper on how the Campbell lab expanded the palette of genetically encoded calcium sensors that modulate fluorescence in response to changes in calcium. An Expanded Palette of Genetically Encoded Ca2+...
