Oct4 – Yamanaka Factors – #Y0020N

Oct4, or Octamer binding transcription factor 4,  forms a complex with Sox2.  It is thought to be crucial in maintaining self renewal in stem cells.  The RefSeq for the human sequence is:  NM_001285987.1

Advantages to using BacMam for Yamanaka Factor expression:

• Adjust the expression levels of the factors by simply adjusting the amount of the BacMam you add to the culture.
• Adjust the relative amounts of  transcription factor expression  by adjusting the ratio of the different amounts of the different BacMam viruses you add.
• Transduce the cells multiple times, over multiple days, to produce prolonged expression.
• The BacMam vector produces transient, integration free expression.
• BacMam vectors are shelf stable in the refrigerator for over a year.
• BacMam vectors are cost effective.  Each of our products contains 10 mls of virus at 2 * 10e10 viral genes per ml, exceeding competitors Lentivirus products by orders of magnitude.