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Targeting the Primary Cilium

Targeting the Primary Cilium

It is now well appreciated that crucial signaling pathways are located in the cilia.  Hedgehog, Wnt, and Notch signaling all occurs in the cilia (Wheway et al., 2018).  Importantly, there is specialized G-protein receptor signaling in the cilia.  For example, the...

SLAS 2019

Tweets by @livecellassays Search for Assay Products Search for: Search Archives Archives Select Month February 2019 January 2019 December 2018 November 2018 August 2018 June 2018 May 2018 September 2017 July 2017 June 2017 April 2017 February 2017 January 2017...
Lee Lab illuminates cAMP signaling in macrophages

Lee Lab illuminates cAMP signaling in macrophages

The Lee Lab at University of Pennsylvania is a diverse group of cell biologists who combine their unique scientific perspectives to the better understanding of airway disease physiology and taste perception. In other words, this lab knows the nose and is enthusiastic...

MT Molecular at ASCB 2018

Watching Biased Agonism at GPCRs in real time. Presented by A.M. Quinn | Montana MolecularSun. Dec. 9, 12 – 1:30 pmPoster# 1558 | B571 Cell Stress Biosensors for Rapid, Live-Cell Detection of Neurotoxic and Cardiotoxic Compounds in iPSC-Derived Neurons and...

Get a New Perspective on Gi Signaling

Robust Gi assay that, in real time, directly reports Gi mediated reductions in cAMP, across a variety of receptors and cell types on standard fluorescence plate readers or imaging systems. Simple, No cell lysis, No FRET, Single channel Can be targeted to specific...
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