The latest developments in GPCR-Based Drug Discovery is coming to Discovery on Target in Boston this week!

  • Learn about kinetic analysis and why monitoring GPCR signaling dynamics is so important.
  • Quantify biased agonism reliably. 
  • Meet Sam Hoare from Pharmechanics and Paul Tewson from Montana Molecular.

Poster presentations:

Poster #307 “Real-Time Kinetic Analysis of GPCR Signaling in Stable PathHunter® Cell Line”
Paul Tewson, Senior Scientist, Montana Molecular
Wednesday, Thrusday September 18
2:00-2:45 pm
4:25-5:00 pm
Thursday September 19
10:15 – 10:55 am
1:25 – 2:05 pm
Poster #309 “A new pharmacological method for quantifying signaling kinetics and biased agonism.”
Sam Hoare, Founder, Pharmechanics
Wednesday, September 18
2:00-2:45 pm
4:25-5:00 pm
Thursday September 19
10:15 – 10:55 am
1:25 – 2:05 pm


Breakout Session:

GPCR-Based Drug Discovery Breakout Session
Moderator: Sam Hoare, PhD, Founder, Pharmechanics LLC
Thursday September 19, 2019 7:30am

  • Compound residence time vs. compound in vivo efficacy
  • Off rate and duration of action
  • Kinetic artifacts in SAR assays

Can’t make the meeting? Request your poster copy: [email protected]