Montana Molecular News
SARS-CoV-2 Variant Pseudoviruses
At Montana Molecular, we are committed to developing validated tools and services to support COVID-19 drug discovery. 2nd generation pseudoviruses for SARS-CoV-2 variants are on the way. Emerging SARS CoV-2 VariantsIn the spring of 2020, Manaus Brazil, was...
Covid 19 Drug Discovery Services
Functional Cell-based Assays Verified & Compound Libraries This unique platform is a powerful resource for researchers developing 3CLpro inhibitors and can streamline the development of safe and effective therapeutic treatments for...
Mpro inhibitor saves cats from certain death
Feline Infectious Peritonitis (FIP) is caused by a coronavirus. The 3CLpro of this virus is much like the one in SARS-CoV-2 and is crucial for viral replication. In 2016, Kim and colleagues showed that the compound GC376 blocked viral replication in cats...
SARS-CoV-2 Neutralization Assay
Screen neutralizing antibodies that inhibit SARS-CoV-2 host cell entry
SARS-CoV-2 Pseudovirus Entry Assay
Overview of SARS-CoV-2 Viral Entry The generally accepted model for SARS-CoV-2 viral entry involves two crucial elements: the Spike protein on the surface of the enveloped virus, and the host receptor ACE2. The Spike protein has a high...
SARS-CoV-2 Pseudovirus (Update)
Thank you for your interest in Montana Molecular’s assays for SARS-CoV-2 research and drug discovery. In a rapidly evolving field, as new insights into the mechanisms of viral entry come to light, we sincerely appreciate your patience and feedback as we continue to...
Live Cell Assays for COVID-19 Drug Screening
COVID-19 continues to disrupt life as we know it, but here in Montana we are devising a new brand of biosensors for our heroes who are testing antivirals to fight SARS-CoV-2. Here’s what’s in our pipeline for targeting viral entry into host cells. ...
BPS 2020 Annual Meeting
We're hosting a booth (#121) and poster at BPS 2020 Annual Meeting in San Diego this week: Poster Presentation 2232-Pos, Board B502 Neurodegenerative Disease and cAMP Signaling Dynamics Tues. Feb. 18, 2:45-3:45 PM Company About Us News Contact Us Careers Connect with...
SLAS 2020 International Conference & Exhibition
We're hosting a booth and poster at SLAS 2020 International Conference & Exhibition in San Diego this week: Poster Presentation 1018-D Live Cell Assays Reveal New Patterns of Cell Signaling in Neurodegenerative Mutants Tues. Jan 28 5:00-6:00 PM Company About Us...
Society for Neuroscience 2019 – Poster Presentation
We know it’s early in the morning, and late in the #SfN2019 week, but don’t miss your chance to meet up with Scott Martinka, Senior Scientist and assay developer at Montana Molecular. Ask Scott to tell you all about this new kinetic method for measuring...
