Montana Molecular News
ArcLight Voltage Sensor
ArcLight Voltage Sensor[fruitful_sep] A genetically-encoded, fluorescent voltage sensing protein in a BacMam viral delivery system is a noninvasive, easy-to-use tool for studying the electrical activity of live neurons. To learn more about the development of voltage...
FPX Biosensors for Live Cell Imaging Published
First there was FRET, now there is FPX
Drug Discovery News
Biotek Scientific Director likes Montana Molecular’s live cell assays: “These sensors can be used for the simultaneous detection of all these second messengers. That is something that is really unique and really powerful, specifically for drug discovery efforts for GPCRs.”
PHASE II SBIR Funding Awarded to Montana Molecular
$1.1 million investment from the National Institutes of Health advances next generation tools for drug discovery in living cells. Montana Molecular, a privately-held company developing next generation tools for drug discovery in living cells, has been...
DAG sensor and μ-opioid receptor desensitization
Early adopters of Montana Molecular’s DAG sensor at The Vollum Institute published new results in the British Journal of Pharmacology. This study made good use of our Upward DAG sensor for diacylglycerol…
DAG sensor illuminates TRPC6 Regulation
Montana Molecular’s DAG sensor helped unravel the molecular mechanisms of TRPC6 cation channel activity which could lead to new treatments for TRPC6-associated diseases that affect cardiovascular and kidney dysfunction…
Wondering about BacMam in your favorite cell type?
BacMam technology is evolving and transduction efficiencies have improved substantially since many of these pioneering papers were published. This body of work provides a summary of what has been accomplished and a starting point for assay optimization in...
Biotek and Montana Molecular Collaborate
Montana Molecular’s assays are ideal for measuring GPCR activity on Biotek’s fluorescence plate readers! In fact, we screen and optimize all of our fluorescent assays in-house on our Biotek Synergy MX. We were curious about the new …
GEN article highlights GPCR assays from Montana Molecular
Wondering what new cell based assays are available for screening in primary cells? Need to detect ligand bias? Wishing you could measure more than one second messenger with an easy multiplex assay? Tired of multistep lytic assays for cAMP? Please...
Montana Molecular DAG sensor paper exceeds 4000 views
DAG biosensors in PLoS. Montana Molecular is very proud to announce that our PLoS paper, Simultaneous Detection of Ca2+ and Diacylglycerol Signaling in Living Cells, has now been downloaded over 4000 times! We appreciate all who have taken the time...
