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Olfactory GPCRs Upregulated in Cancer

Olfactory GPCRs Upregulated in Cancer

Olfactory GPCRs Upregulated in Cancer OR51E1 and OR51E2 linked to cell growth The Sweet Smell of a NobelThirty years ago, Linda Buck and Richard Axel described a large family of genes that encode what appeared to be G-protein coupled receptors, or GPCRs. These genes...
A Rapid and Sensitive Approach to Detecting SARS-CoV-2

A Rapid and Sensitive Approach to Detecting SARS-CoV-2

A Rapid and Sensitive Approach to Detecting SARS-CoV-2 Gold Nanoparticles Enable Rapid SARS-CoV-2 Detection and Inhibition There is a race in this pandemic to develop new technologies to detect SAR-CoV-2 virus and defeat its spread as quickly as possible. A bright...
Measuring partial and biased agonism at GPCRs on the FDSS/μCell

Measuring partial and biased agonism at GPCRs on the FDSS/μCell

Measuring partial and biased agonism at GPCRs on the FDSS/μCell Kinetic analysis to measure agonist bias Montana Molecular’s genetically-encoded, fluorescent biosensors detect multiple receptor-mediated signaling pathways in real-time, live-cell assays. The kinetics...
The Neuroscience of Nausea

The Neuroscience of Nausea

The Neuroscience of Nausea The elusive area postrema  Nausea is a sense of malaise that all of us know. The sensation can be so overpowering that it leads us to wonder how and why this wretched condition  happens. Researchers in Stephen Liberles’ lab at Harvard...
SARS-CoV-2 Variant Pseudoviruses

SARS-CoV-2 Variant Pseudoviruses

At Montana Molecular, we are committed to developing validated tools and services to support COVID-19 drug discovery. 2nd generation pseudoviruses for SARS-CoV-2 variants are on the way. Emerging SARS CoV-2 VariantsIn the spring of 2020, Manaus Brazil, was hit hard by...
Covid 19 Drug Discovery Services

Covid 19 Drug Discovery Services

Functional Cell-based Assays Verified & Compound Libraries  This unique platform is a powerful resource for researchers developing 3CLpro inhibitors and can streamline the development of safe and effective therapeutic treatments for COVID-19. OTAVAchemicals and...