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3CLglow Assay (C1160G)

$695.00$3,895.00

A live cell assay for SARS-CoV-2 3CLpro enzyme inhibition and activity.


Featured Publication:

A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron subvariants

 

SARS-CoV-2 assays and reagents

3CLpro (Mpro) Inhibitor Assay

The 3CLglow Assay kit includes 2 BacMam viruses. One expresses the 3CLpro enzyme, the other expresses a green fluorescent biosensor for 3CLpro enzyme activity as well as a red fluorescent protein to control for compound toxicity.

  • Identify protease inhibitors that target SARS-CoV-2 replication
  • Cost effective screening with minimal safety requirements (BSL-1)

Materials in the Kit:

• Green Fluorescent 3CLpro reporter in BacMam (3CLglow BacMam)

• 3CLpro Enzyme in BacMam

• Sodium Butyrate, 500 mM in H2O

 

Additional information

Protocol for Use

https://montanamolecular.com/covid-19-reagents/3clglow-assay-protocol/

Shipping

We strive for prompt delivery of each order, so we ship by FedEx 2-day service in lightweight, sturdy, and reusable/biodegradable packaging with an insulated cooler and moisture-resistant refrigerant gel packs. Shipping days are Mon-Wed so product does not sit in transit over the weekend. Web store ships to US & Canada only, contact sales for other locations.

MSDS

https://montanamolecular.com/msds-for-sars-cov-2-reagents/

Kit Volume

5mL, 30mL, 60mL

More Info

https://montanamolecular.com/covid-19-reagents/3clglow/

COVID-19 tools Publications
Pseudovirus and Host Factor Publications
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