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#C1150N Cathepsin L

$395.00$795.00

Human Cathepsin L in a BacMam vector for controlled CATL1 expression in a wide variety of cell types.

Cathepsin-L (CATL1)

Express Human Cathepsin L using a BacMam for efficient delivery to practically any cell type. There is recent evidence that Cathepsin L can play a role in SARS-CoV-2 viral entry.

Recent papers:

Huang, I-Chueh, Berend Jan Bosch, Fang Li, Wenhui Li, Kyoung Hoa Lee, Sorina Ghiran, Natalya Vasilieva, et al. 2006. “SARS Coronavirus, but Not Human Coronavirus NL63, Utilizes Cathepsin L to Infect ACE2-Expressing Cells.The Journal of Biological Chemistry 281 (6): 3198–3203.

Ou, Xiuyuan, Yan Liu, Xiaobo Lei, Pei Li, Dan Mi, Lili Ren, Li Guo, et al. 2020. “Characterization of Spike Glycoprotein of SARS-CoV-2 on Virus Entry and Its Immune Cross-Reactivity with SARS-CoV.” Nature Communications 11 (1): 1620.


Materials in the Kit:

• Cathepsin-L BacMam

• Sodium Butyrate, 500 mM in H2O

Additional information

Protocol for Use

https://montanamolecular.com/general-bacmam-transduction-protocol/

Shipping

We strive for prompt delivery of each order, so we ship by FedEx 2-day service in lightweight, sturdy, and reusable/biodegradable packaging with an insulated cooler and moisture-resistant refrigerant gel packs. Shipping days are Mon-Wed so product does not sit in transit over the weekend. Web store ships to US & Canada only, contact sales for other locations.

MSDS

https://montanamolecular.com/msds-for-sars-cov-2-reagents/

Reference Sequence

AAX36816.1

More Info

https://montanamolecular.com/covid-19-reagents/host-factors-for-sars-cov-2-entry/

Kit Volume

5mL, 30mL