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Painting the Omegasome

Painting the Omegasome

Visualize proteostasis and autophagy processes in living cells with a fluorescent probe Green OmegaPaint is a new addition to our suite of Cell Painting tools, combining the bright mNeonGreen fluorescent protein with a portion of the DFCP1 protein (Double FYVE...
Express RAMPs with BacMam

Express RAMPs with BacMam

BacMam-packaged human RAMP1, RAMP2, and RAMP3 are now available from Montana Molecular! Receptor Activity-Modifying Proteins (RAMPs) can regulate the function and specificity of G-protein-coupled receptors – influencing their trafficking, ligand selectivity, and...
Introducing Big Sky BacMam

Introducing Big Sky BacMam

Introducing Big Sky BacMam The R&D team at Montana Molecular has been hard at work improving our BacMam vector! We’re excited to release Big Sky BacMam – a vector which, in our hands, yields greatly improved transduction efficiency in HEK and CHO...
Detecting inhibitors of mutant 3CL proteases

Detecting inhibitors of mutant 3CL proteases

Find your next-generation SARS-CoV-2 inhibitor using mutant 3CL proteases The SARS-CoV-2 protease is crucial to virus replication. If the main protease, known as 3CLpro can be blocked, the virus can be stopped. The commonly prescribed Paxlovid contains a 3CLpro...
Montana Paintbrush

Montana Paintbrush

Montana Paintbrush Montana Paintbrush (Paintbrush, MT Paintbrush) is a bright, rapidly folding red fluorescent protein developed at Montana Molecular. It is nearly twice as bright as mCherry 24 hours after transduction as seen in Figure 1 below. Figure 1: Fluorescence...
Next-generation drugs for the evolving SARS-CoV-2 virus

Next-generation drugs for the evolving SARS-CoV-2 virus

Next-generation drugs for the evolving SARS-CoV-2 virus There is increasing evidence that new variants of SARS-CoV-2 are appearing that cannot be treated with Paxlovid.  This means that the next generation of antivirals will soon be needed to reduce the severity of...
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