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SARS-CoV-2 Host Factors

Host Cell Factors for SARS-CoV-2 Viral Entry Host Factors for Viral Entry  Spike protein on SARS-CoV-2 interacts with the ACE2 receptor on the host cell to initiate viral entry, but other host factors are also involved. While ACE2 is necessary, it does not appear to...

SARS-CoV-2 Pseudovirus Entry Assay

SARS-CoV-2 Pseudovirus Entry Assay

Overview of SARS-CoV-2 Viral Entry The generally accepted model for SARS-CoV-2 viral entry involves two crucial elements: the Spike protein on the surface of the enveloped virus, and the host receptor ACE2.  The Spike protein has a high...

SARS-CoV-2 Pseudovirus (Update)

SARS-CoV-2 Pseudovirus (Update)

Thank you for your interest in Montana Molecular’s assays for SARS-CoV-2 research and drug discovery. In a rapidly evolving field, as new insights into the mechanisms of viral entry come to light, we sincerely appreciate your patience and feedback as we continue to...

Scientific Publications

PublicationsPublications by Product L. Bridge, et al. Computational modelling of dynamic cAMP responses to GPCR agonists for exploration of GLP-1R ligand effects in pancreatic β-cells and neurons. Cellular Signaling, April 2024. R. Fagan, et al. Selective targeting of...